实验室利用结构生物学和生物化学等多种手段，从事植物RNA结合蛋白的结构与功能研究，旨在揭示植物生长发育和逆境应答中的RNA代谢调控作用，为植物特别是作物发育研究提供理论基础和技术支持。

一，RNA代谢相关蛋白质机器结构解析

最新研究成果

Wang X#, Feng J#, Xue Y#, Guan Z, Zhang D, Liu Z, Gong Z, Wang Q, Huang J, Tang C, Zou T, Yin P*. Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex. Nature. 2016 May 25. doi: 10.1038/nature18298.点击查看

二，RNA识别工具开发

最新研究成果

Shen C#, Wang X#, Liu Y, Li Q, Yang Z, Yan N, Zou T, Yin P*. Specific RNA recognition by designer pentatricopeptide repeat protein. Mol Plant. 2015 Apr;8(4):667-70点击查看

Shen C#, Zhang D#, Guan Z#, Liu Y, Yang Z, Yang Y, Wang X, Wang Q, Zhang Q, Fan S, Zou T, Yin P*. Structural basis for the specific single-stranded RNA recognition by designer pentatricopeptide repeat protein. Nat. Commun. 2016 Apr 18;7:11285.点击查看

Yin P#, Li Q#, Yan C, Liu Y, Liu J, Yu F, Wang Z, Long J, He J, Wang H, Wang J, Zhu J, Shi Y, Yan N*. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature.2013 Dec 5; 504 (7478): 168-171.

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三，脱落酸类似物设计

最新研究成果

He Y, Hao Q, Li W, Yan C, Yan N*, Yin P*. Identification and characterization of ABA receptors in Oryza sativa. PloS ONE. 2014 Apr 17; 9(4): e95246.点击查看

Hao Q#, Yin P#, Li W, Wang L, Yan C, Lin Z, Wu JZ, Wang J, Yan SF, Yan N*. The molecular basis of ABA-independent inhibition of PP2Cs by a subclass of PYL proteins. Mol Cell. 2011 Jun 10;42(5):662-72点击查看